EBS Seminar: Molecular Dialogues with the Microbiota in the Zebrafish Intestine

Cancelled due to illness

Title: Molecular Dialogues with the Microbiota in the Zebrafish Intestine
Speaker: Karen Guillemin

Location: OHSU West Campus
20000 N.W. Walker Road on Von Neumann Drive
Paul Clayton Building, Room PC401

Dr. Karen Guillemin is an Associate Professor of Biology at the University of Oregon, and a member of the Institute of Molecular Biology

She received her B.A. from Harvard and Radcliffe Colleges and her Ph.D. from Stanford University.

Research Interests:

All animals exist in intimate associations with communities of microorganisms that play important roles in the hosts' normal development and physiology, and under certain circumstances can cause disease. The Guillemin lab investigates the molecular dialogues between bacteria and host cells that promote normal tissue development or cause pathology. The laboratory focuses on two experimental models. To understand the mechanisms by which intimate, long-term bacterial-host cell interactions can detrimentally alter host tissue programs of development and homeostasis, they study Helicobacter pylori, a pathogen of the human stomach that is associated with a number of diseases including gastric cancer. To understand the benefits that microbial associations confer on animals, they have pioneered a germ-free zebrafish model that allows them to precisely define the contributions of the resident microbiota to development of this model vertebrate.